Prague is an easy destination to get to. It is served by Ruzyně International Airport, which is the hub of the flag carrier, Czech Airlines.

There are several cheap flights per day from the UK and from other countries. Ruzyně International Airport is considered as one of the most modern airports in Europe.

Public transport infrastructure consists of an integrated transport system of three metro lines (with 54 stations in total), trams, Prague Tram System (including the "nostalgic tram" no. 91), buses, a funicular to Petřín Hill and a chairlift at Prague Zoo.

All services have a common ticketing system, and are run by Dopravní podnik hl. m. Prahy (The Capital City of Prague Transport Company).The "nostalgic tram" no. 91 runs through the city centre.

The city forms the hub of the Czech railway system, with services to all parts of the Czech Republic and to neighbouring countries. Prague has two international railway stations, Hlavní nádraží (sometimes referred to as Wilsonovo nádraží) and Praha Holešovice.

Intercity services also stop at the main stations Praha Smíchov and Masarykovo nádraží. In addition to these, there are a number of smaller suburban stations.

The Jerusalem Synagogue, built in 1906 to 1907 by Wilhelm Stiassny, of Bratislava, is the largest Jewish place of worship in Prague. The taxi service in Prague has had a somewhat checkered history. During the rule of Communist Party in Czechoslovakia (1948–1989), the taxi service was nationalised into one umbrella company, and, with a short exception during liberalization related to the Prague Spring, no independent taxi drivers were allowed.

The quality and availability of the service was low. This caused many enterprising people to run illegal taxi services. Their earnings were far above income of typical citizens and became a source of envy. After the fall of the Communist regime, the service was liberalized and anyone could become a taxi driver. Unfortunately, the chaos of transition from planned to market economy did not leave any time to implement sufficient regulations.

The lack of planning and controls has led to a number of serious taxi scams operating in the city; some of which have been linked with organised crime. Many of the victims of overpricing are tourists. Taxi services in Prague can currently be divided into three sectors.

There are major taxicab companies, operating call-for-taxi services (radio-taxi) or from regulated taxi stands, where overpricing is rare and regulation mostly in place. There are independent drivers, who make pick-ups on the street; cheating is mostly associated with these cars. Lastly, there are fake taxi drivers, who operate as "contractual transport services" in order to avoid government regulation.